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Allylic hydroxylation of enones useful for the functionalization of relevant drugs and natural products
Enones are privileged structural motifs in bioactive natural products and pharmaceuticals, but the γ-hydroxylation of enones is challenging. Here we show a mild and efficient method for the direct C(sp(3))–H hydroxylation of enones via visible-light-induced hydrogen-atom transfer (HAT), which facili...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133259/ https://www.ncbi.nlm.nih.gov/pubmed/37100800 http://dx.doi.org/10.1038/s41467-023-38154-9 |