Cell surface-localized CsgF condensate is a gatekeeper in bacterial curli subunit secretion

Curli are functional amyloids present on the outer membrane of E. coli. CsgF is required for the proper assembly of curli. Here, we found that the CsgF phase separates in vitro and that the ability of CsgF variants to phase-separate is tightly correlated with CsgF function during curli biogenesis. S...

Descripción completa

Detalles Bibliográficos
Autores principales: Swasthi, Hema M., Basalla, Joseph L., Dudley, Claire E., Vecchiarelli, Anthony G., Chapman, Matthew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133297/
https://www.ncbi.nlm.nih.gov/pubmed/37100792
http://dx.doi.org/10.1038/s41467-023-38089-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133297/
https://www.ncbi.nlm.nih.gov/pubmed/37100792
http://dx.doi.org/10.1038/s41467-023-38089-1

Ejemplares similares