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Cell surface-localized CsgF condensate is a gatekeeper in bacterial curli subunit secretion
Curli are functional amyloids present on the outer membrane of E. coli. CsgF is required for the proper assembly of curli. Here, we found that the CsgF phase separates in vitro and that the ability of CsgF variants to phase-separate is tightly correlated with CsgF function during curli biogenesis. S...
Autores principales: | Swasthi, Hema M., Basalla, Joseph L., Dudley, Claire E., Vecchiarelli, Anthony G., Chapman, Matthew R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133297/ https://www.ncbi.nlm.nih.gov/pubmed/37100792 http://dx.doi.org/10.1038/s41467-023-38089-1 |
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