Intravitreal injection of fibrillin 2 (Fbn2) recombinant protein for therapy of retinopathy in a retina-specific Fbn2 knock-down mouse model

Mutations in the extracellular matrix gene Fibrillin-2 (FBN2) are related to genetic macular degenerative disorders including age-related macular degeneration (AMD) and early-onset macular degeneration (EOMD). It was reported that the retinal protein expression of FBN2 was reduced in patients with A...

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Detalles Bibliográficos
Autores principales: Zhang, Rui Xue, Wen, Ying, Guo, Da Dong, Xu, Fu Ru, Wang, Gui Min, Wang, Xing Rong, Shi, Yong Wei, Ding, Jie, Jiang, Qian, Jiang, Wen Jun, Jonas, Jost B., Bi, Hong Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133334/
https://www.ncbi.nlm.nih.gov/pubmed/37100863
http://dx.doi.org/10.1038/s41598-023-33886-6

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