Scalable continuous-flow electroporation platform enabling T cell transfection for cellular therapy manufacturing

Viral vectors represent a bottleneck in the manufacturing of cellular therapies. Electroporation has emerged as an approach for non-viral transfection of primary cells, but standard cuvette-based approaches suffer from low throughput, difficult optimization, and incompatibility with large-scale cell...

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Detalles Bibliográficos
Autores principales: VanderBurgh, Jacob A., Corso, Thomas N., Levy, Stephen L., Craighead, Harold G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133335/
https://www.ncbi.nlm.nih.gov/pubmed/37185305
http://dx.doi.org/10.1038/s41598-023-33941-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133335/
https://www.ncbi.nlm.nih.gov/pubmed/37185305
http://dx.doi.org/10.1038/s41598-023-33941-2

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