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Scalable continuous-flow electroporation platform enabling T cell transfection for cellular therapy manufacturing
Viral vectors represent a bottleneck in the manufacturing of cellular therapies. Electroporation has emerged as an approach for non-viral transfection of primary cells, but standard cuvette-based approaches suffer from low throughput, difficult optimization, and incompatibility with large-scale cell...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133335/ https://www.ncbi.nlm.nih.gov/pubmed/37185305 http://dx.doi.org/10.1038/s41598-023-33941-2 |