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Expanding the pH range of glutamate decarboxylase from L. pltarum LC84 by site-directed mutagenesis

Introduction: Glutamate decarboxylase is a class Ⅱ amino acid decarboxylase dependent onpyridoxal-5′-phosphate (PLP), which catalyzes the decarboxylation of substrateL-glutamate (L-Glu) to synthesize γ-aminobutyric acid (GABA). The low activity ofglutamic acid decarboxylase (GAD) and its ability to...

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Detalles Bibliográficos
Autores principales:	Yang, Lijuan, Zhang, Xian, Chen, Jing, Zhang, Yao, Feng, Zhiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133459/ https://www.ncbi.nlm.nih.gov/pubmed/37122870 http://dx.doi.org/10.3389/fbioe.2023.1160818

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