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Successful treatment of idiopathic retinal vasculitis with rituximab in two patients
PURPOSE: To describe results of treatment of idiopathic retinal vasculitis with intravenous rituximab. OBSERVATIONS: We present two patients with idiopathic retinal vasculitis who required steroid-sparing therapy and achieved steroid-free remission with intravenous rituximab. Rituximab was used as a...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133649/ https://www.ncbi.nlm.nih.gov/pubmed/37124152 http://dx.doi.org/10.1016/j.ajoc.2023.101844 |
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author | Apivatthakakul, Atitaya Liu, Renee Sobrin, Lucia |
author_facet | Apivatthakakul, Atitaya Liu, Renee Sobrin, Lucia |
author_sort | Apivatthakakul, Atitaya |
collection | PubMed |
description | PURPOSE: To describe results of treatment of idiopathic retinal vasculitis with intravenous rituximab. OBSERVATIONS: We present two patients with idiopathic retinal vasculitis who required steroid-sparing therapy and achieved steroid-free remission with intravenous rituximab. Rituximab was used as a first-line steroid-sparing agent after steroids in one patient and as a second-line steroid-sparing agent in the other patient. Both patients achieved steroid-free remission of disease with follow up of at least one year after rituximab initiation. CONCLUSIONS AND IMPORTANCE: Rituximab achieved steroid-free remission in two patients with idiopathic retinal vasculitis. It should be considered as a treatment option in these patients. |
format | Online Article Text |
id | pubmed-10133649 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-101336492023-04-28 Successful treatment of idiopathic retinal vasculitis with rituximab in two patients Apivatthakakul, Atitaya Liu, Renee Sobrin, Lucia Am J Ophthalmol Case Rep Case Report PURPOSE: To describe results of treatment of idiopathic retinal vasculitis with intravenous rituximab. OBSERVATIONS: We present two patients with idiopathic retinal vasculitis who required steroid-sparing therapy and achieved steroid-free remission with intravenous rituximab. Rituximab was used as a first-line steroid-sparing agent after steroids in one patient and as a second-line steroid-sparing agent in the other patient. Both patients achieved steroid-free remission of disease with follow up of at least one year after rituximab initiation. CONCLUSIONS AND IMPORTANCE: Rituximab achieved steroid-free remission in two patients with idiopathic retinal vasculitis. It should be considered as a treatment option in these patients. Elsevier 2023-04-12 /pmc/articles/PMC10133649/ /pubmed/37124152 http://dx.doi.org/10.1016/j.ajoc.2023.101844 Text en © 2023 The Authors. Published by Elsevier Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Apivatthakakul, Atitaya Liu, Renee Sobrin, Lucia Successful treatment of idiopathic retinal vasculitis with rituximab in two patients |
title | Successful treatment of idiopathic retinal vasculitis with rituximab in two patients |
title_full | Successful treatment of idiopathic retinal vasculitis with rituximab in two patients |
title_fullStr | Successful treatment of idiopathic retinal vasculitis with rituximab in two patients |
title_full_unstemmed | Successful treatment of idiopathic retinal vasculitis with rituximab in two patients |
title_short | Successful treatment of idiopathic retinal vasculitis with rituximab in two patients |
title_sort | successful treatment of idiopathic retinal vasculitis with rituximab in two patients |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133649/ https://www.ncbi.nlm.nih.gov/pubmed/37124152 http://dx.doi.org/10.1016/j.ajoc.2023.101844 |
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