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Successful treatment of idiopathic retinal vasculitis with rituximab in two patients

PURPOSE: To describe results of treatment of idiopathic retinal vasculitis with intravenous rituximab. OBSERVATIONS: We present two patients with idiopathic retinal vasculitis who required steroid-sparing therapy and achieved steroid-free remission with intravenous rituximab. Rituximab was used as a...

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Detalles Bibliográficos
Autores principales: Apivatthakakul, Atitaya, Liu, Renee, Sobrin, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133649/
https://www.ncbi.nlm.nih.gov/pubmed/37124152
http://dx.doi.org/10.1016/j.ajoc.2023.101844
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author Apivatthakakul, Atitaya
Liu, Renee
Sobrin, Lucia
author_facet Apivatthakakul, Atitaya
Liu, Renee
Sobrin, Lucia
author_sort Apivatthakakul, Atitaya
collection PubMed
description PURPOSE: To describe results of treatment of idiopathic retinal vasculitis with intravenous rituximab. OBSERVATIONS: We present two patients with idiopathic retinal vasculitis who required steroid-sparing therapy and achieved steroid-free remission with intravenous rituximab. Rituximab was used as a first-line steroid-sparing agent after steroids in one patient and as a second-line steroid-sparing agent in the other patient. Both patients achieved steroid-free remission of disease with follow up of at least one year after rituximab initiation. CONCLUSIONS AND IMPORTANCE: Rituximab achieved steroid-free remission in two patients with idiopathic retinal vasculitis. It should be considered as a treatment option in these patients.
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spelling pubmed-101336492023-04-28 Successful treatment of idiopathic retinal vasculitis with rituximab in two patients Apivatthakakul, Atitaya Liu, Renee Sobrin, Lucia Am J Ophthalmol Case Rep Case Report PURPOSE: To describe results of treatment of idiopathic retinal vasculitis with intravenous rituximab. OBSERVATIONS: We present two patients with idiopathic retinal vasculitis who required steroid-sparing therapy and achieved steroid-free remission with intravenous rituximab. Rituximab was used as a first-line steroid-sparing agent after steroids in one patient and as a second-line steroid-sparing agent in the other patient. Both patients achieved steroid-free remission of disease with follow up of at least one year after rituximab initiation. CONCLUSIONS AND IMPORTANCE: Rituximab achieved steroid-free remission in two patients with idiopathic retinal vasculitis. It should be considered as a treatment option in these patients. Elsevier 2023-04-12 /pmc/articles/PMC10133649/ /pubmed/37124152 http://dx.doi.org/10.1016/j.ajoc.2023.101844 Text en © 2023 The Authors. Published by Elsevier Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Apivatthakakul, Atitaya
Liu, Renee
Sobrin, Lucia
Successful treatment of idiopathic retinal vasculitis with rituximab in two patients
title Successful treatment of idiopathic retinal vasculitis with rituximab in two patients
title_full Successful treatment of idiopathic retinal vasculitis with rituximab in two patients
title_fullStr Successful treatment of idiopathic retinal vasculitis with rituximab in two patients
title_full_unstemmed Successful treatment of idiopathic retinal vasculitis with rituximab in two patients
title_short Successful treatment of idiopathic retinal vasculitis with rituximab in two patients
title_sort successful treatment of idiopathic retinal vasculitis with rituximab in two patients
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133649/
https://www.ncbi.nlm.nih.gov/pubmed/37124152
http://dx.doi.org/10.1016/j.ajoc.2023.101844
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