Cargando…
Combined therapy with pioglitazone and FGF21 mRNA synergistically ameliorates metabolic disorders in NAFLD rats
BACKGROUND: Current study aims to investigate the ameliorative effect of pioglitazone (PIO) combined with mRNA encoding FGF21 (termed mFGF21) on the metabolic disorders in rats with nonalcoholic fatty liver disease (NAFLD) and its potential mechanism. METHODS: In vitro functional activity of FGF21 p...
Autores principales: | Huang, Xixia, Xia, Zuyu, Huang, Yiqin, Sun, Yifei, Zhang, Lina, Xiong, Wenjian, Zhang, Ziyan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133668/ https://www.ncbi.nlm.nih.gov/pubmed/37123911 http://dx.doi.org/10.1016/j.heliyon.2023.e15146 |
Ejemplares similares
-
Canagliflozin ameliorates the development of NAFLD by preventing NLRP3-mediated pyroptosis through FGF21-ERK1/2 pathway
por: Huang, Shaohan, et al.
Publicado: (2023) -
Research Perspectives on the Regulation and Physiological Functions of FGF21 and its Association with NAFLD
por: Inagaki, Takeshi
Publicado: (2015) -
Exercise ameliorates the FGF21–adiponectin axis impairment in diet-induced obese mice
por: Yang, Wenqi, et al.
Publicado: (2019) -
FGF21 ameliorates the neurocontrol of blood pressure in the high fructose-drinking rats
por: He, Jian-Li, et al.
Publicado: (2016) -
Recombinant FGF21 Attenuates Polychlorinated Biphenyl-Induced NAFLD/NASH by Modulating Hepatic Lipocalin-2 Expression
por: Kim, Hye Young, et al.
Publicado: (2022)