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Inhibition of phosphoinositide‑3 kinases γ/δ ameliorates pulmonary granuloma by rescuing Treg function in a sarcoidosis model

Sarcoidosis is a multisystem inflammatory disease characterized by the development of Th1/Th17/regulatory T cells (Tregs)-related non-caseating granulomas. Phosphoinositide-3 kinases δ/γ (PI3Kδ/γ) play an important role in the maintenance of effective immunity, especially for Tregs homeostasis and s...

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Detalles Bibliográficos
Autores principales:	Zhang, Xian, Dai, Qianqian, Shan, Jiajia, Zhang, Shiyun, Zhang, Bin, Liu, Siyang, Zhang, Yixue, Wang, Ying, Li, Xiaojie, Jin, Xuguang, Liang, Dongmei, Ding, Jingjing, Wang, Yong, Wen, Yanting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2023
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133787/ https://www.ncbi.nlm.nih.gov/pubmed/37123205 http://dx.doi.org/10.3892/etm.2023.11923

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