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Protocol for infecting and monitoring susceptible k18-hACE2 mice with SARS-CoV-2

Intranasal infection of k18-hACE2 mice with SARS-CoV-2 recapitulates the clinical characteristics present in severe COVID-19. Here, we present a protocol for intranasal administration of SARS-CoV-2 to k18-hACE2 mice and their subsequent daily monitoring. We describe steps for intranasal inoculation...

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Detalles Bibliográficos
Autores principales:	Couto, Joana, Gonçalves, Rute, Lamas, Sofia, Saraiva, Margarida
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10133884/ https://www.ncbi.nlm.nih.gov/pubmed/37178116 http://dx.doi.org/10.1016/j.xpro.2023.102303

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