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Extracellular Vesicles (EVs) in Tumor Diagnosis and Therapy

In recent years, extracellular vesicles (EVs) have gained significant attention due to their tremendous potential for clinical applications. EVs play a crucial role in various aspects, including tumorigenesis, drug resistance, immune escape, and reconstruction of the tumor microenvironment. Despite...

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Detalles Bibliográficos
Autores principales: Tan, Mingdian, Ge, Yizhi, Wang, Xiaogang, Wang, Yan, Liu, Yi, He, Feng, Teng, Hongqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10134167/
https://www.ncbi.nlm.nih.gov/pubmed/37122245
http://dx.doi.org/10.1177/15330338231171463
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author Tan, Mingdian
Ge, Yizhi
Wang, Xiaogang
Wang, Yan
Liu, Yi
He, Feng
Teng, Hongqi
author_facet Tan, Mingdian
Ge, Yizhi
Wang, Xiaogang
Wang, Yan
Liu, Yi
He, Feng
Teng, Hongqi
author_sort Tan, Mingdian
collection PubMed
description In recent years, extracellular vesicles (EVs) have gained significant attention due to their tremendous potential for clinical applications. EVs play a crucial role in various aspects, including tumorigenesis, drug resistance, immune escape, and reconstruction of the tumor microenvironment. Despite the growing interest in EVs, many questions still need to be addressed before they can be practically applied in clinical settings. This paper aims to review EVs’ isolation methods, structure research, the roles of EVs in tumorigenesis and their mechanisms in multiple types of tumors, their potential application in drug delivery, and the expectations for their future in clinical research.
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spelling pubmed-101341672023-04-28 Extracellular Vesicles (EVs) in Tumor Diagnosis and Therapy Tan, Mingdian Ge, Yizhi Wang, Xiaogang Wang, Yan Liu, Yi He, Feng Teng, Hongqi Technol Cancer Res Treat Emerging roles of Extracellular Vesicles in Cancer Research and Therapy In recent years, extracellular vesicles (EVs) have gained significant attention due to their tremendous potential for clinical applications. EVs play a crucial role in various aspects, including tumorigenesis, drug resistance, immune escape, and reconstruction of the tumor microenvironment. Despite the growing interest in EVs, many questions still need to be addressed before they can be practically applied in clinical settings. This paper aims to review EVs’ isolation methods, structure research, the roles of EVs in tumorigenesis and their mechanisms in multiple types of tumors, their potential application in drug delivery, and the expectations for their future in clinical research. SAGE Publications 2023-04-25 /pmc/articles/PMC10134167/ /pubmed/37122245 http://dx.doi.org/10.1177/15330338231171463 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Emerging roles of Extracellular Vesicles in Cancer Research and Therapy
Tan, Mingdian
Ge, Yizhi
Wang, Xiaogang
Wang, Yan
Liu, Yi
He, Feng
Teng, Hongqi
Extracellular Vesicles (EVs) in Tumor Diagnosis and Therapy
title Extracellular Vesicles (EVs) in Tumor Diagnosis and Therapy
title_full Extracellular Vesicles (EVs) in Tumor Diagnosis and Therapy
title_fullStr Extracellular Vesicles (EVs) in Tumor Diagnosis and Therapy
title_full_unstemmed Extracellular Vesicles (EVs) in Tumor Diagnosis and Therapy
title_short Extracellular Vesicles (EVs) in Tumor Diagnosis and Therapy
title_sort extracellular vesicles (evs) in tumor diagnosis and therapy
topic Emerging roles of Extracellular Vesicles in Cancer Research and Therapy
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10134167/
https://www.ncbi.nlm.nih.gov/pubmed/37122245
http://dx.doi.org/10.1177/15330338231171463
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