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Extracellular Vesicles (EVs) in Tumor Diagnosis and Therapy
In recent years, extracellular vesicles (EVs) have gained significant attention due to their tremendous potential for clinical applications. EVs play a crucial role in various aspects, including tumorigenesis, drug resistance, immune escape, and reconstruction of the tumor microenvironment. Despite...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10134167/ https://www.ncbi.nlm.nih.gov/pubmed/37122245 http://dx.doi.org/10.1177/15330338231171463 |
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author | Tan, Mingdian Ge, Yizhi Wang, Xiaogang Wang, Yan Liu, Yi He, Feng Teng, Hongqi |
author_facet | Tan, Mingdian Ge, Yizhi Wang, Xiaogang Wang, Yan Liu, Yi He, Feng Teng, Hongqi |
author_sort | Tan, Mingdian |
collection | PubMed |
description | In recent years, extracellular vesicles (EVs) have gained significant attention due to their tremendous potential for clinical applications. EVs play a crucial role in various aspects, including tumorigenesis, drug resistance, immune escape, and reconstruction of the tumor microenvironment. Despite the growing interest in EVs, many questions still need to be addressed before they can be practically applied in clinical settings. This paper aims to review EVs’ isolation methods, structure research, the roles of EVs in tumorigenesis and their mechanisms in multiple types of tumors, their potential application in drug delivery, and the expectations for their future in clinical research. |
format | Online Article Text |
id | pubmed-10134167 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-101341672023-04-28 Extracellular Vesicles (EVs) in Tumor Diagnosis and Therapy Tan, Mingdian Ge, Yizhi Wang, Xiaogang Wang, Yan Liu, Yi He, Feng Teng, Hongqi Technol Cancer Res Treat Emerging roles of Extracellular Vesicles in Cancer Research and Therapy In recent years, extracellular vesicles (EVs) have gained significant attention due to their tremendous potential for clinical applications. EVs play a crucial role in various aspects, including tumorigenesis, drug resistance, immune escape, and reconstruction of the tumor microenvironment. Despite the growing interest in EVs, many questions still need to be addressed before they can be practically applied in clinical settings. This paper aims to review EVs’ isolation methods, structure research, the roles of EVs in tumorigenesis and their mechanisms in multiple types of tumors, their potential application in drug delivery, and the expectations for their future in clinical research. SAGE Publications 2023-04-25 /pmc/articles/PMC10134167/ /pubmed/37122245 http://dx.doi.org/10.1177/15330338231171463 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Emerging roles of Extracellular Vesicles in Cancer Research and Therapy Tan, Mingdian Ge, Yizhi Wang, Xiaogang Wang, Yan Liu, Yi He, Feng Teng, Hongqi Extracellular Vesicles (EVs) in Tumor Diagnosis and Therapy |
title | Extracellular Vesicles (EVs) in Tumor Diagnosis and Therapy |
title_full | Extracellular Vesicles (EVs) in Tumor Diagnosis and Therapy |
title_fullStr | Extracellular Vesicles (EVs) in Tumor Diagnosis and Therapy |
title_full_unstemmed | Extracellular Vesicles (EVs) in Tumor Diagnosis and Therapy |
title_short | Extracellular Vesicles (EVs) in Tumor Diagnosis and Therapy |
title_sort | extracellular vesicles (evs) in tumor diagnosis and therapy |
topic | Emerging roles of Extracellular Vesicles in Cancer Research and Therapy |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10134167/ https://www.ncbi.nlm.nih.gov/pubmed/37122245 http://dx.doi.org/10.1177/15330338231171463 |
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