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Influence of Cysteine 440 on the Active Site Properties of 3-Deoxy-d-Arabino-Heptulosonate 7-Phosphate Synthase in Mycobacterium tuberculosis (MtDAHPS)

[Image: see text] The shikimate pathway, which produces aromatic amino acids and key intermediates, is critical to the viability of the tuberculosis-causing pathogen Mycobacterium tuberculosis. The enzyme 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase (DAHPS) catalyzes the first committed step...

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Detalles Bibliográficos
Autores principales:	Faponle, Abayomi S., Fagbohunka, Bamidele S., Gauld, James W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10134247/ https://www.ncbi.nlm.nih.gov/pubmed/37125090 http://dx.doi.org/10.1021/acsomega.2c07662

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