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Isolation, Structural Elucidation of a New Triterpenoid from the Roots of Jasminum sambac (L.) Ait. with Potent Cytotoxicity against MCF-7 Cell Lines
[Image: see text] A new triterpenoid was isolated from the roots of Jasminum sambac (L.) Ait. Its structure was elucidated by 1D and 2D NMR analysis, single crystal X-ray diffraction, and HRESIMS. This compound exhibited potent in vitro anticancer efficacy against MCF-7 cell lines with IC(50)’s of 1...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10134469/ https://www.ncbi.nlm.nih.gov/pubmed/37125138 http://dx.doi.org/10.1021/acsomega.3c00544 |
| Sumario: | [Image: see text] A new triterpenoid was isolated from the roots of Jasminum sambac (L.) Ait. Its structure was elucidated by 1D and 2D NMR analysis, single crystal X-ray diffraction, and HRESIMS. This compound exhibited potent in vitro anticancer efficacy against MCF-7 cell lines with IC(50)’s of 193.5 μM for 24 h and 154.6 μM for 48 h. |
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