Isolation, Structural Elucidation of a New Triterpenoid from the Roots of Jasminum sambac (L.) Ait. with Potent Cytotoxicity against MCF-7 Cell Lines

[Image: see text] A new triterpenoid was isolated from the roots of Jasminum sambac (L.) Ait. Its structure was elucidated by 1D and 2D NMR analysis, single crystal X-ray diffraction, and HRESIMS. This compound exhibited potent in vitro anticancer efficacy against MCF-7 cell lines with IC(50)’s of 1...

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Autores principales: Olatunde, Olagoke Zacchaeus, Yong, Jianping, Lu, Canzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10134469/
https://www.ncbi.nlm.nih.gov/pubmed/37125138
http://dx.doi.org/10.1021/acsomega.3c00544
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author Olatunde, Olagoke Zacchaeus
Yong, Jianping
Lu, Canzhong
author_facet Olatunde, Olagoke Zacchaeus
Yong, Jianping
Lu, Canzhong
author_sort Olatunde, Olagoke Zacchaeus
collection PubMed
description [Image: see text] A new triterpenoid was isolated from the roots of Jasminum sambac (L.) Ait. Its structure was elucidated by 1D and 2D NMR analysis, single crystal X-ray diffraction, and HRESIMS. This compound exhibited potent in vitro anticancer efficacy against MCF-7 cell lines with IC(50)’s of 193.5 μM for 24 h and 154.6 μM for 48 h.
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spelling pubmed-101344692023-04-28 Isolation, Structural Elucidation of a New Triterpenoid from the Roots of Jasminum sambac (L.) Ait. with Potent Cytotoxicity against MCF-7 Cell Lines Olatunde, Olagoke Zacchaeus Yong, Jianping Lu, Canzhong ACS Omega [Image: see text] A new triterpenoid was isolated from the roots of Jasminum sambac (L.) Ait. Its structure was elucidated by 1D and 2D NMR analysis, single crystal X-ray diffraction, and HRESIMS. This compound exhibited potent in vitro anticancer efficacy against MCF-7 cell lines with IC(50)’s of 193.5 μM for 24 h and 154.6 μM for 48 h. American Chemical Society 2023-04-12 /pmc/articles/PMC10134469/ /pubmed/37125138 http://dx.doi.org/10.1021/acsomega.3c00544 Text en © 2023 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by-nc-nd/4.0/Permits non-commercial access and re-use, provided that author attribution and integrity are maintained; but does not permit creation of adaptations or other derivative works (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Olatunde, Olagoke Zacchaeus
Yong, Jianping
Lu, Canzhong
Isolation, Structural Elucidation of a New Triterpenoid from the Roots of Jasminum sambac (L.) Ait. with Potent Cytotoxicity against MCF-7 Cell Lines
title Isolation, Structural Elucidation of a New Triterpenoid from the Roots of Jasminum sambac (L.) Ait. with Potent Cytotoxicity against MCF-7 Cell Lines
title_full Isolation, Structural Elucidation of a New Triterpenoid from the Roots of Jasminum sambac (L.) Ait. with Potent Cytotoxicity against MCF-7 Cell Lines
title_fullStr Isolation, Structural Elucidation of a New Triterpenoid from the Roots of Jasminum sambac (L.) Ait. with Potent Cytotoxicity against MCF-7 Cell Lines
title_full_unstemmed Isolation, Structural Elucidation of a New Triterpenoid from the Roots of Jasminum sambac (L.) Ait. with Potent Cytotoxicity against MCF-7 Cell Lines
title_short Isolation, Structural Elucidation of a New Triterpenoid from the Roots of Jasminum sambac (L.) Ait. with Potent Cytotoxicity against MCF-7 Cell Lines
title_sort isolation, structural elucidation of a new triterpenoid from the roots of jasminum sambac (l.) ait. with potent cytotoxicity against mcf-7 cell lines
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10134469/
https://www.ncbi.nlm.nih.gov/pubmed/37125138
http://dx.doi.org/10.1021/acsomega.3c00544
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