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The impact of PIK3CA mutations and PTEN expression on the effect of neoadjuvant therapy for postmenopausal luminal breast cancer patients

BACKGROUND: There is pressing needs to find the biomarker in the selection of neoadjuvant therapy in postmenopausal luminal breast cancer patients. We examined the hypothesis that PIK3CA mutations and low phosphatase and tensin homolog (PTEN) expression affect the response to neoadjuvant therapy and...

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Detalles Bibliográficos
Autores principales: Hayama, Shouko, Nakamura, Rikiya, Ishige, Takayuki, Sangai, Takafumi, Sakakibara, Masahiro, Fujimoto, Hiroshi, Ishigami, Emi, Masuda, Takahito, Nakagawa, Ayako, Teranaka, Ryotaro, Ota, Satoshi, Itoga, Sakae, Yamamoto, Naohito, Nagashima, Takeshi, Otsuka, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10134571/
https://www.ncbi.nlm.nih.gov/pubmed/37106324
http://dx.doi.org/10.1186/s12885-023-10853-y

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