Prominent epigenetic and transcriptomic changes in CD4(+) and CD8(+) T cells during and after pregnancy in women with multiple sclerosis and controls

BACKGROUND: Multiple sclerosis (MS) is a neuroinflammatory disease in which pregnancy leads to a temporary amelioration in disease activity as indicated by the profound decrease in relapses rate during the 3rd trimester of pregnancy. CD4(+) and CD8(+) T cells are implicated in MS pathogenesis as bei...

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Detalles Bibliográficos
Autores principales: Zenere, Alberto, Hellberg, Sandra, Papapavlou Lingehed, Georgia, Svenvik, Maria, Mellergård, Johan, Dahle, Charlotte, Vrethem, Magnus, Raffetseder, Johanna, Khademi, Mohsen, Olsson, Tomas, Blomberg, Marie, Jenmalm, Maria C., Altafini, Claudio, Gustafsson, Mika, Ernerudh, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10134602/
https://www.ncbi.nlm.nih.gov/pubmed/37106402
http://dx.doi.org/10.1186/s12974-023-02781-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10134602/
https://www.ncbi.nlm.nih.gov/pubmed/37106402
http://dx.doi.org/10.1186/s12974-023-02781-2

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