Cargando…

Down-regulation of ERAP1 mRNA expression in non-small cell lung cancer

BACKGROUND: ERAP1 is a major aminopeptidase that serves as an editor of the peptide repertoire by trimming N-terminal residues of antigenic peptides, creating a pool of peptides with the optimal length for MHC-I binding. As an important component of the antigen processing and presenting machinery –...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wagner, Marta, Sobczyński, Maciej, Jasek, Monika, Pawełczyk, Konrad, Porębska, Irena, Kuśnierczyk, Piotr, Wiśniewski, Andrzej
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10134604/ https://www.ncbi.nlm.nih.gov/pubmed/37101107 http://dx.doi.org/10.1186/s12885-023-10785-7

Ejemplares similares

Polymorphisms of Antigen-Presenting Machinery Genes in Non-Small Cell Lung Cancer: Different Impact on Disease Risk and Clinical Parameters in Smokers and Never-Smokers
por: Wiśniewski, Andrzej, et al.
Publicado: (2021)

The association of BTLA gene polymorphisms with non-small lung cancer risk in smokers and never-smokers
por: Andrzejczak, Anna, et al.
Publicado: (2023)

Single Nucleotide Polymorphisms of the ERAP1 Gene and Risk of NSCLC: A Comparison of Genetically Distant Populations, Chinese and Caucasian
por: Yao, Yufeng, et al.
Publicado: (2017)

Common inherited variants of PDCD1, CD274 and HAVCR2 genes differentially modulate the risk and prognosis of adenocarcinoma and squamous cell carcinoma
por: Moksud, Nafeesa, et al.
Publicado: (2023)

Preliminary Study on the Role of TMEM39A Gene in Multiple Sclerosis
por: Wagner, Marta, et al.
Publicado: (2017)

Association of variants in BAFF (rs9514828 and rs1041569) and BAFF-R (rs61756766) genes with the risk of chronic lymphocytic leukemia
por: Jasek, Monika, et al.
Publicado: (2016)

ERAP, KIR, and HLA-C Profile in Recurrent Implantation Failure
por: Piekarska, Karolina, et al.
Publicado: (2021)

Human leukocyte antigen (HLA)-G gene polymorphism in patients with non-small cell lung cancer
por: Kowal, Aneta, et al.
Publicado: (2015)

Serum and Whole Blood Cu and Zn Status in Predicting Mortality in Lung Cancer Patients
por: Zabłocka-Słowińska, Katarzyna, et al.
Publicado: (2020)

Systemic redox status in lung cancer patients is related to altered glucose metabolism
por: Zabłocka-Słowińska, Katarzyna, et al.
Publicado: (2018)

Serum Total SOD Activity and SOD1/2 Concentrations in Predicting All-Cause Mortality in Lung Cancer Patients
por: Skórska, Katarzyna Beata, et al.
Publicado: (2021)

Oxidative stress in lung cancer patients is associated with altered serum markers of lipid metabolism
por: Zabłocka-Słowińska, Katarzyna, et al.
Publicado: (2019)

Association of Common Variants of TNFSF13 and TNFRSF13B Genes with CLL Risk and Clinical Picture, as Well as Expression of Their Products—APRIL and TACI Molecules
por: Jasek, Monika, et al.
Publicado: (2020)

Polymorphisms in ERAP1 and ERAP2 Genes Are Associated With Tuberculosis in the Han Chinese
por: Zhang, Shuqiong, et al.
Publicado: (2020)

Total antioxidant status in lung cancer is associated with levels of endogenous antioxidants and disease stage rather than lifestyle factors – preliminary study
por: Zabłocka-Słowińska, Katarzyna, et al.
Publicado: (2016)

The Multifaceted Nature of Aminopeptidases ERAP1, ERAP2, and LNPEP: From Evolution to Disease
por: Paladini, Fabiana, et al.
Publicado: (2020)

The Differential Expression of ERAP1/ERAP2 and Immune Cell Activation in Pre-eclampsia
por: Seamon, Kimberly, et al.
Publicado: (2020)

Genetic association of ERAP1 and ERAP2 with eclampsia and preeclampsia in northeastern Brazilian women
por: Ferreira, Leonardo Capistrano, et al.
Publicado: (2021)

The ER Aminopeptidases, ERAP1 and ERAP2, synergize to self-modulate their respective activities
por: Martín-Esteban, Adrian, et al.
Publicado: (2022)

How ERAP1 and ERAP2 Shape the Peptidomes of Disease-Associated MHC-I Proteins
por: López de Castro, José A.
Publicado: (2018)

ERAP1 and ERAP2 Enzymes: A Protective Shield for RAS against COVID-19?
por: D’Amico, Silvia, et al.
Publicado: (2021)

Can ERAP1 and ERAP2 Form Functional Heterodimers? A Structural Dynamics Investigation
por: Papakyriakou, Athanasios, et al.
Publicado: (2022)

The methylenetetrahydrofolate reductase c.c.677 C>T and c.c.1298 A>C polymorphisms in reproductive failures: Experience from an RSA and RIF study on a Polish population
por: Nowak, Izabela, et al.
Publicado: (2017)

The impact of HLA-G, LILRB1 and LILRB2 gene polymorphisms on susceptibility to and severity of endometriosis
por: Bylińska, Aleksandra, et al.
Publicado: (2017)

ERAP1/ERAP2 and RUNX3 polymorphisms are not associated with ankylosing spondylitis susceptibility in Chinese Han
por: Su, W., et al.
Publicado: (2018)

Functionally distinct ERAP1 and ERAP2 are a hallmark of HLA-A29-(Birdshot) Uveitis
por: Kuiper, Jonas J W, et al.
Publicado: (2018)

Associations of Genes for Killer Cell Immunoglobulin-like Receptors and Their Human Leukocyte Antigen-A/B/C Ligands with Abdominal Aortic Aneurysm
por: Dubis, Joanna, et al.
Publicado: (2021)

An Overview on ERAP Roles in Infectious Diseases
por: Saulle, Irma, et al.
Publicado: (2020)

An allelic variant in the intergenic region between ERAP1 and ERAP2 correlates with an inverse expression of the two genes
por: Paladini, Fabiana, et al.
Publicado: (2018)

Concerted In Vitro Trimming of Viral HLA-B27-Restricted Ligands by Human ERAP1 and ERAP2 Aminopeptidases
por: Lorente, Elena, et al.
Publicado: (2013)

ERAP1-ERAP2 dimers trim MHC I-bound precursor peptides; implications for understanding peptide editing
por: Chen, Hanna, et al.
Publicado: (2016)

The emerging multifunctional roles of ERAP1, ERAP2 and IRAP between antigen processing and renin-angiotensin system modulation
por: Mattorre, Benedetta, et al.
Publicado: (2022)

The role of polymorphic ERAP1 in autoinflammatory disease
por: Reeves, Emma, et al.
Publicado: (2018)

A novel ERAP2 haplotype structure in a Chilean population: implications for ERAP2 protein expression and preeclampsia risk
por: Vanhille, Derek L, et al.
Publicado: (2013)

A novel ERAP2 haplotype structure in a Chilean population: implications for ERAP2 protein expression and preeclampsia risk
por: Vanhille, Derek L, et al.
Publicado: (2013)

The Impact of the ‘Mis-Peptidome’ on HLA Class I-Mediated Diseases: Contribution of ERAP1 and ERAP2 and Effects on the Immune Response
por: Tedeschi, Valentina, et al.
Publicado: (2020)

Haplotype dependent association of rs7927894 (11q13.5) with atopic dermatitis and chronic allergic rhinitis: A study in ECAP cohort
por: Ponińska, Joanna Kinga, et al.
Publicado: (2017)

HLA-C*06:02-independent, gender-related association of PSORS1C3 and PSORS1C1/CDSN single-nucleotide polymorphisms with risk and severity of psoriasis
por: Wiśniewski, Andrzej, et al.
Publicado: (2018)

ERAP/HLA-C and KIR Genetic Profile in Couples with Recurrent Implantation Failure
por: Piekarska, Karolina, et al.
Publicado: (2022)

Evaluation of new classifications of N descriptor in non-small cell lung cancer (NSCLC) based on the number and the ratio of metastatic lymph nodes
por: Pawełczyk, Konrad, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_0njobieu9mh97ks80e9k7hm3lr