Limiting Mrs2-dependent mitochondrial Mg(2+) uptake induces metabolic programming in prolonged dietary stress

The most abundant cellular divalent cations, Mg(2+) (mM) and Ca(2+) (nM-μM), antagonistically regulate divergent metabolic pathways with several orders of magnitude affinity preference, but the physiological significance of this competition remains elusive. In mice consuming a Western diet, genetic...

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Detalles Bibliográficos
Autores principales: Madaris, Travis R., Venkatesan, Manigandan, Maity, Soumya, Stein, Miriam C., Vishnu, Neelanjan, Venkateswaran, Mridula K., Davis, James G., Ramachandran, Karthik, Uthayabalan, Sukanthathulse, Allen, Cristel, Osidele, Ayodeji, Stanley, Kristen, Bigham, Nicholas P., Bakewell, Terry M., Narkunan, Melanie, Le, Amy, Karanam, Varsha, Li, Kang, Mhapankar, Aum, Norton, Luke, Ross, Jean, Aslam, M. Imran, Reeves, W. Brian, Singh, Brij B., Caplan, Jeffrey, Wilson, Justin J., Stathopulos, Peter B., Baur, Joseph A., Madesh, Muniswamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10134742/
https://www.ncbi.nlm.nih.gov/pubmed/36857182
http://dx.doi.org/10.1016/j.celrep.2023.112155

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