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A Cysteine-Reloading Process Initiating the Biosynthesis of the Bicyclic Scaffold of Dithiolopyrrolones

Dithiolopyrrolone antibiotics are well known for their outstanding biological activities, and their biosynthesis has been studied vigorously. However, the biosynthesis mechanism of the characteristic bicyclic scaffold is still unknown after years of research. To uncover this mechanism, a multi-domai...

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Detalles Bibliográficos
Autores principales: Chen, Yan, Tu, Yanqin, Pan, Tingyu, Deng, Zixin, Duan, Lian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10134970/
https://www.ncbi.nlm.nih.gov/pubmed/37107148
http://dx.doi.org/10.3390/antibiotics12040787

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