Cargando…
Dynamics-Based Regulatory Switches of Type II Antitoxins: Insights into New Antimicrobial Discovery
Type II toxin-antitoxin (TA) modules are prevalent in prokaryotes and are involved in cell maintenance and survival under harsh environmental conditions, including nutrient deficiency, antibiotic treatment, and human immune responses. Typically, the type II TA system consists of two protein componen...
Autores principales: | Lee, Ki-Young, Lee, Bong-Jin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135005/ https://www.ncbi.nlm.nih.gov/pubmed/37106997 http://dx.doi.org/10.3390/antibiotics12040637 |
Ejemplares similares
-
The DarT/DarG Toxin–Antitoxin ADP-Ribosylation System as a Novel Target for a Rational Design of Innovative Antimicrobial Strategies
por: Catara, Giuliana, et al.
Publicado: (2023) -
Structure, Biology, and Therapeutic Application of Toxin–Antitoxin Systems in Pathogenic Bacteria
por: Lee, Ki-Young, et al.
Publicado: (2016) -
Keeping the Wolves at Bay: Antitoxins of Prokaryotic Type II Toxin-Antitoxin Systems
por: Chan, Wai Ting, et al.
Publicado: (2016) -
Iron regulatory protein 1: the deadly switch of ferroptosis
por: Bórquez, Daniel A., et al.
Publicado: (2023) -
Structural and functional studies of the Mycobacterium tuberculosis VapBC30 toxin-antitoxin system: implications for the design of novel antimicrobial peptides
por: Lee, In-Gyun, et al.
Publicado: (2015)