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Fast and Sensitive Method for Simultaneous Quantification of Meropenem and Vaborbactam in Human Plasma Microsamples by Liquid Chromatography–Tandem Mass Spectrometry for Therapeutic Drug Monitoring
Meropenem (MRP)-Vaborbactam (VBR) is a novel beta-lactam/beta-lactamase inhibitor used for the management of difficult-to-treat Gram-negative infections. Among critically ill patients, MRP-VBR shows remarkable inter-individual variability in pharmacokinetic behavior, thus justifying the implementati...
Autores principales: | Barone, Rossella, Conti, Matteo, Giorgi, Beatrice, Gatti, Milo, Cojutti, Pier Giorgio, Viale, Pierluigi, Pea, Federico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135283/ https://www.ncbi.nlm.nih.gov/pubmed/37107082 http://dx.doi.org/10.3390/antibiotics12040719 |
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