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Studying and Analyzing Humane Endpoints in the Fructose-Fed and Streptozotocin-Injected Rat Model of Diabetes
SIMPLE SUMMARY: This study assessed a humane endpoint scoring system to detect animal suffering in a rat model of type 2 diabetes. Sprague-Dawley male rats were divided into control and induced (fructose-fed and streptozotocin (STZ) administration) groups. Induced animals drank 10% fructose for 14 d...
Autores principales: | Silva-Reis, Rita, Faustino-Rocha, Ana I., Silva, Jéssica, Valada, Abigaël, Azevedo, Tiago, Anjos, Lara, Gonçalves, Lio, Pinto, Maria de Lurdes, Ferreira, Rita, Silva, Artur M. S., Cardoso, Susana M., Oliveira, Paula A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135389/ https://www.ncbi.nlm.nih.gov/pubmed/37106960 http://dx.doi.org/10.3390/ani13081397 |
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