Enhancing the Conformational Stability of the cl-Par-4 Tumor Suppressor via Site-Directed Mutagenesis

Intrinsically disordered proteins play important roles in cell signaling, and dysregulation of these proteins is associated with several diseases. Prostate apoptosis response-4 (Par-4), an approximately 40 kilodalton proapoptotic tumor suppressor, is a predominantly intrinsically disordered protein...

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Detalles Bibliográficos
Autores principales: Pandey, Samjhana, Raut, Krishna K., Clark, Andrea M., Baudin, Antoine, Djemri, Lamya, Libich, David S., Ponniah, Komala, Pascal, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135485/
https://www.ncbi.nlm.nih.gov/pubmed/37189414
http://dx.doi.org/10.3390/biom13040667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135485/
https://www.ncbi.nlm.nih.gov/pubmed/37189414
http://dx.doi.org/10.3390/biom13040667

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