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Enhancing the Conformational Stability of the cl-Par-4 Tumor Suppressor via Site-Directed Mutagenesis

Intrinsically disordered proteins play important roles in cell signaling, and dysregulation of these proteins is associated with several diseases. Prostate apoptosis response-4 (Par-4), an approximately 40 kilodalton proapoptotic tumor suppressor, is a predominantly intrinsically disordered protein...

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Detalles Bibliográficos
Autores principales:	Pandey, Samjhana, Raut, Krishna K., Clark, Andrea M., Baudin, Antoine, Djemri, Lamya, Libich, David S., Ponniah, Komala, Pascal, Steven M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135485/ https://www.ncbi.nlm.nih.gov/pubmed/37189414 http://dx.doi.org/10.3390/biom13040667

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