Characterization of Adenylyl Cyclase Isoform 6 Residues Interacting with Forskolin

SIMPLE SUMMARY: Adenylyl cyclase isoform 6 is the only member of the adenylyl cyclase enzyme family to be inhibited by low oxygen levels. We studied the unique structure of the adenylyl cyclase 6 molecule, using computer models that draw upon known adenylyl cyclase structures. We also mutated severa...

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Detalles Bibliográficos
Autores principales: Bhatia, Vikram, Maghsoudi, Saeid, Hinton, Martha, Bhagirath, Anjali Y., Singh, Nisha, Jaggupilli, Appalaraju, Chelikani, Prashen, Dakshinamurti, Shyamala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135528/
https://www.ncbi.nlm.nih.gov/pubmed/37106773
http://dx.doi.org/10.3390/biology12040572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135528/
https://www.ncbi.nlm.nih.gov/pubmed/37106773
http://dx.doi.org/10.3390/biology12040572

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