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Classification and Antigen Molecules of Autoimmune Bullous Diseases

Autoimmune bullous diseases (AIBDs), which are a group of tissue-specific autoimmune diseases of the skin, present with various blistering lesions on the skin and mucous membranes, and show autoantibodies of IgG, IgA and IgM against epidermal cell surfaces and basement membrane zone. To date, AIBDs...

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Detalles Bibliográficos
Autores principales: Hashimoto, Takashi, Qian, Hua, Ishii, Norito, Nakama, Takekuni, Tateishi, Chiharu, Tsuruta, Daisuke, Li, Xiaoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135556/
https://www.ncbi.nlm.nih.gov/pubmed/37189450
http://dx.doi.org/10.3390/biom13040703
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author Hashimoto, Takashi
Qian, Hua
Ishii, Norito
Nakama, Takekuni
Tateishi, Chiharu
Tsuruta, Daisuke
Li, Xiaoguang
author_facet Hashimoto, Takashi
Qian, Hua
Ishii, Norito
Nakama, Takekuni
Tateishi, Chiharu
Tsuruta, Daisuke
Li, Xiaoguang
author_sort Hashimoto, Takashi
collection PubMed
description Autoimmune bullous diseases (AIBDs), which are a group of tissue-specific autoimmune diseases of the skin, present with various blistering lesions on the skin and mucous membranes, and show autoantibodies of IgG, IgA and IgM against epidermal cell surfaces and basement membrane zone. To date, AIBDs have been classified into a number of distinct subtypes by clinical and histopathological findings, and immunological characteristics. In addition, various biochemical and molecular biological studies have identified various novel autoantigens in AIBDs, which has resulted in proposals of new subtypes of AIBDs. In this article, we summarized various distinct AIBDs, and proposed the latest and most comprehensive classification of AIBDs with their autoantigen molecules.
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spelling pubmed-101355562023-04-28 Classification and Antigen Molecules of Autoimmune Bullous Diseases Hashimoto, Takashi Qian, Hua Ishii, Norito Nakama, Takekuni Tateishi, Chiharu Tsuruta, Daisuke Li, Xiaoguang Biomolecules Review Autoimmune bullous diseases (AIBDs), which are a group of tissue-specific autoimmune diseases of the skin, present with various blistering lesions on the skin and mucous membranes, and show autoantibodies of IgG, IgA and IgM against epidermal cell surfaces and basement membrane zone. To date, AIBDs have been classified into a number of distinct subtypes by clinical and histopathological findings, and immunological characteristics. In addition, various biochemical and molecular biological studies have identified various novel autoantigens in AIBDs, which has resulted in proposals of new subtypes of AIBDs. In this article, we summarized various distinct AIBDs, and proposed the latest and most comprehensive classification of AIBDs with their autoantigen molecules. MDPI 2023-04-20 /pmc/articles/PMC10135556/ /pubmed/37189450 http://dx.doi.org/10.3390/biom13040703 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Hashimoto, Takashi
Qian, Hua
Ishii, Norito
Nakama, Takekuni
Tateishi, Chiharu
Tsuruta, Daisuke
Li, Xiaoguang
Classification and Antigen Molecules of Autoimmune Bullous Diseases
title Classification and Antigen Molecules of Autoimmune Bullous Diseases
title_full Classification and Antigen Molecules of Autoimmune Bullous Diseases
title_fullStr Classification and Antigen Molecules of Autoimmune Bullous Diseases
title_full_unstemmed Classification and Antigen Molecules of Autoimmune Bullous Diseases
title_short Classification and Antigen Molecules of Autoimmune Bullous Diseases
title_sort classification and antigen molecules of autoimmune bullous diseases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135556/
https://www.ncbi.nlm.nih.gov/pubmed/37189450
http://dx.doi.org/10.3390/biom13040703
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