Cargando…
Classification and Antigen Molecules of Autoimmune Bullous Diseases
Autoimmune bullous diseases (AIBDs), which are a group of tissue-specific autoimmune diseases of the skin, present with various blistering lesions on the skin and mucous membranes, and show autoantibodies of IgG, IgA and IgM against epidermal cell surfaces and basement membrane zone. To date, AIBDs...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135556/ https://www.ncbi.nlm.nih.gov/pubmed/37189450 http://dx.doi.org/10.3390/biom13040703 |
_version_ | 1785032007769653248 |
---|---|
author | Hashimoto, Takashi Qian, Hua Ishii, Norito Nakama, Takekuni Tateishi, Chiharu Tsuruta, Daisuke Li, Xiaoguang |
author_facet | Hashimoto, Takashi Qian, Hua Ishii, Norito Nakama, Takekuni Tateishi, Chiharu Tsuruta, Daisuke Li, Xiaoguang |
author_sort | Hashimoto, Takashi |
collection | PubMed |
description | Autoimmune bullous diseases (AIBDs), which are a group of tissue-specific autoimmune diseases of the skin, present with various blistering lesions on the skin and mucous membranes, and show autoantibodies of IgG, IgA and IgM against epidermal cell surfaces and basement membrane zone. To date, AIBDs have been classified into a number of distinct subtypes by clinical and histopathological findings, and immunological characteristics. In addition, various biochemical and molecular biological studies have identified various novel autoantigens in AIBDs, which has resulted in proposals of new subtypes of AIBDs. In this article, we summarized various distinct AIBDs, and proposed the latest and most comprehensive classification of AIBDs with their autoantigen molecules. |
format | Online Article Text |
id | pubmed-10135556 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-101355562023-04-28 Classification and Antigen Molecules of Autoimmune Bullous Diseases Hashimoto, Takashi Qian, Hua Ishii, Norito Nakama, Takekuni Tateishi, Chiharu Tsuruta, Daisuke Li, Xiaoguang Biomolecules Review Autoimmune bullous diseases (AIBDs), which are a group of tissue-specific autoimmune diseases of the skin, present with various blistering lesions on the skin and mucous membranes, and show autoantibodies of IgG, IgA and IgM against epidermal cell surfaces and basement membrane zone. To date, AIBDs have been classified into a number of distinct subtypes by clinical and histopathological findings, and immunological characteristics. In addition, various biochemical and molecular biological studies have identified various novel autoantigens in AIBDs, which has resulted in proposals of new subtypes of AIBDs. In this article, we summarized various distinct AIBDs, and proposed the latest and most comprehensive classification of AIBDs with their autoantigen molecules. MDPI 2023-04-20 /pmc/articles/PMC10135556/ /pubmed/37189450 http://dx.doi.org/10.3390/biom13040703 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Hashimoto, Takashi Qian, Hua Ishii, Norito Nakama, Takekuni Tateishi, Chiharu Tsuruta, Daisuke Li, Xiaoguang Classification and Antigen Molecules of Autoimmune Bullous Diseases |
title | Classification and Antigen Molecules of Autoimmune Bullous Diseases |
title_full | Classification and Antigen Molecules of Autoimmune Bullous Diseases |
title_fullStr | Classification and Antigen Molecules of Autoimmune Bullous Diseases |
title_full_unstemmed | Classification and Antigen Molecules of Autoimmune Bullous Diseases |
title_short | Classification and Antigen Molecules of Autoimmune Bullous Diseases |
title_sort | classification and antigen molecules of autoimmune bullous diseases |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135556/ https://www.ncbi.nlm.nih.gov/pubmed/37189450 http://dx.doi.org/10.3390/biom13040703 |
work_keys_str_mv | AT hashimototakashi classificationandantigenmoleculesofautoimmunebullousdiseases AT qianhua classificationandantigenmoleculesofautoimmunebullousdiseases AT ishiinorito classificationandantigenmoleculesofautoimmunebullousdiseases AT nakamatakekuni classificationandantigenmoleculesofautoimmunebullousdiseases AT tateishichiharu classificationandantigenmoleculesofautoimmunebullousdiseases AT tsurutadaisuke classificationandantigenmoleculesofautoimmunebullousdiseases AT lixiaoguang classificationandantigenmoleculesofautoimmunebullousdiseases |