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Increased Circulating Osteopontin Levels Promote Primary Tumour Growth, but Do Not Induce Metastasis in Melanoma

Osteopontin (OPN) is a phosphoprotein with diverse functions in various physiological and pathological processes. OPN expression is increased in multiple cancers, and OPN within tumour tissue has been shown to promote key stages of cancer development. OPN levels are also elevated in the circulation...

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Detalles Bibliográficos
Autores principales: Saup, Rafael, Nair, Nidhi, Shen, Jingyi, Schmaus, Anja, Thiele, Wilko, Garvalov, Boyan K., Sleeman, Jonathan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135562/
https://www.ncbi.nlm.nih.gov/pubmed/37189656
http://dx.doi.org/10.3390/biomedicines11041038