Does Enhanced Structural Maturity of hiPSC-Cardiomyocytes Better for the Detection of Drug-Induced Cardiotoxicity?

Human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) are currently used following the Comprehensive in vitro Proarrhythmic Assay (CiPA) initiative and subsequent recommendations in the International Council for Harmonization (ICH) guidelines S7B and E14 Q&A, to detect drug-indu...

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Detalles Bibliográficos
Autores principales: Van de Sande, Dieter, Ghasemi, Mohammadreza, Watters, Taylor, Burton, Francis, Pham, Ly, Altrocchi, Cristina, Gallacher, David J., Lu, Huarong, Smith, Godfrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135569/
https://www.ncbi.nlm.nih.gov/pubmed/37189424
http://dx.doi.org/10.3390/biom13040676

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135569/
https://www.ncbi.nlm.nih.gov/pubmed/37189424
http://dx.doi.org/10.3390/biom13040676

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