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The Use of Wound Infiltration for Postoperative Pain Management after Breast Cancer Surgery: A Randomized Clinical Study

(1) Background: The present study aims to evaluate the reduction of postoperative pain in breast surgery using a series of local analgesics, which were infiltrated into the wound; (2) Methods: Envelopes containing allocation were prepared prior to the study. The patients involved were randomly assig...

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Autores principales: Faur, Flaviu Ionut, Clim, Ioana Adelina, Dobrescu, Amadeus, Isaic, Alexandru, Prodan, Catalin, Florea, Sabrina, Tarta, Cristi, Totolici, Bogdan, Duţă, Ciprian, Pasca, Paul, Lazar, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135600/
https://www.ncbi.nlm.nih.gov/pubmed/37189812
http://dx.doi.org/10.3390/biomedicines11041195
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author Faur, Flaviu Ionut
Clim, Ioana Adelina
Dobrescu, Amadeus
Isaic, Alexandru
Prodan, Catalin
Florea, Sabrina
Tarta, Cristi
Totolici, Bogdan
Duţă, Ciprian
Pasca, Paul
Lazar, Gabriel
author_facet Faur, Flaviu Ionut
Clim, Ioana Adelina
Dobrescu, Amadeus
Isaic, Alexandru
Prodan, Catalin
Florea, Sabrina
Tarta, Cristi
Totolici, Bogdan
Duţă, Ciprian
Pasca, Paul
Lazar, Gabriel
author_sort Faur, Flaviu Ionut
collection PubMed
description (1) Background: The present study aims to evaluate the reduction of postoperative pain in breast surgery using a series of local analgesics, which were infiltrated into the wound; (2) Methods: Envelopes containing allocation were prepared prior to the study. The patients involved were randomly assigned to the groups of local anesthesia infiltration (Group A) or normal pain management with intravenous analgesics (Group B). The random allocation sequence was generated using computer-generated random numbers. The normally distributed continuous data were expressed as the means (SD) and were assessed using the analysis of variance (ANOVA), independent-sample t-test, or paired t-test; (3) Results: The development of the postoperative pain stages was recorded using the VAS score. Therefore, for Group A, the following results were obtained: the VAS at 6 h postoperatively showed an average value of 0.63 and a maximum value of 3. The results for Group B were the following: the VAS score at 6 h postoperatively showed an average value of 4.92, a maximum of 8, and a minimum of 2; (4) Conclusions: We can confirm that there are favorable statistical indicators regarding the postoperative pain management process during the first 24–38 h after a surgical intervention for breast cancer using local infiltration of anesthetics.
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spelling pubmed-101356002023-04-28 The Use of Wound Infiltration for Postoperative Pain Management after Breast Cancer Surgery: A Randomized Clinical Study Faur, Flaviu Ionut Clim, Ioana Adelina Dobrescu, Amadeus Isaic, Alexandru Prodan, Catalin Florea, Sabrina Tarta, Cristi Totolici, Bogdan Duţă, Ciprian Pasca, Paul Lazar, Gabriel Biomedicines Article (1) Background: The present study aims to evaluate the reduction of postoperative pain in breast surgery using a series of local analgesics, which were infiltrated into the wound; (2) Methods: Envelopes containing allocation were prepared prior to the study. The patients involved were randomly assigned to the groups of local anesthesia infiltration (Group A) or normal pain management with intravenous analgesics (Group B). The random allocation sequence was generated using computer-generated random numbers. The normally distributed continuous data were expressed as the means (SD) and were assessed using the analysis of variance (ANOVA), independent-sample t-test, or paired t-test; (3) Results: The development of the postoperative pain stages was recorded using the VAS score. Therefore, for Group A, the following results were obtained: the VAS at 6 h postoperatively showed an average value of 0.63 and a maximum value of 3. The results for Group B were the following: the VAS score at 6 h postoperatively showed an average value of 4.92, a maximum of 8, and a minimum of 2; (4) Conclusions: We can confirm that there are favorable statistical indicators regarding the postoperative pain management process during the first 24–38 h after a surgical intervention for breast cancer using local infiltration of anesthetics. MDPI 2023-04-17 /pmc/articles/PMC10135600/ /pubmed/37189812 http://dx.doi.org/10.3390/biomedicines11041195 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Faur, Flaviu Ionut
Clim, Ioana Adelina
Dobrescu, Amadeus
Isaic, Alexandru
Prodan, Catalin
Florea, Sabrina
Tarta, Cristi
Totolici, Bogdan
Duţă, Ciprian
Pasca, Paul
Lazar, Gabriel
The Use of Wound Infiltration for Postoperative Pain Management after Breast Cancer Surgery: A Randomized Clinical Study
title The Use of Wound Infiltration for Postoperative Pain Management after Breast Cancer Surgery: A Randomized Clinical Study
title_full The Use of Wound Infiltration for Postoperative Pain Management after Breast Cancer Surgery: A Randomized Clinical Study
title_fullStr The Use of Wound Infiltration for Postoperative Pain Management after Breast Cancer Surgery: A Randomized Clinical Study
title_full_unstemmed The Use of Wound Infiltration for Postoperative Pain Management after Breast Cancer Surgery: A Randomized Clinical Study
title_short The Use of Wound Infiltration for Postoperative Pain Management after Breast Cancer Surgery: A Randomized Clinical Study
title_sort use of wound infiltration for postoperative pain management after breast cancer surgery: a randomized clinical study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135600/
https://www.ncbi.nlm.nih.gov/pubmed/37189812
http://dx.doi.org/10.3390/biomedicines11041195
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