Cargando…

Oscillating Glucose Induces the Increase in Inflammatory Stress through Ninjurin-1 Up-Regulation and Stimulation of Transport Proteins in Human Endothelial Cells

Clinical data implicate fluctuations of high levels of plasma glucose in cardiovascular diseases. Endothelial cells (EC) are the first cells of the vessel wall exposed to them. Our aim was to evaluate the effects of oscillating glucose (OG) on EC function and to decipher new molecular mechanisms inv...

Descripción completa

Detalles Bibliográficos
Autores principales:	Toma, Laura, Sanda, Gabriela M., Stancu, Camelia S., Niculescu, Loredan S., Raileanu, Mina, Sima, Anca V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135653/ https://www.ncbi.nlm.nih.gov/pubmed/37189375 http://dx.doi.org/10.3390/biom13040626

Ejemplares similares

CRISPR/dCas9 Transcriptional Activation of Endogenous Apolipoprotein AI and Paraoxonase 1 in Enterocytes Alleviates Endothelial Cell Dysfunction
por: Toma, Laura, et al.
Publicado: (2021)

Aggregated LDL turn human macrophages into foam cells and induce mitochondrial dysfunction without triggering oxidative or endoplasmic reticulum stress
por: Sanda, Gabriela M., et al.
Publicado: (2021)

Phenolic Compounds Exerting Lipid-Regulatory, Anti-Inflammatory and Epigenetic Effects as Complementary Treatments in Cardiovascular Diseases
por: Toma, Laura, et al.
Publicado: (2020)

Mitochondrial DNA Together with miR-142-3p in Plasma Can Predict Unfavorable Outcomes in Patients after Acute Myocardial Infarction
por: Barbalata, Teodora, et al.
Publicado: (2022)

Elevated Levels of Circulating lncRNAs LIPCAR and MALAT1 Predict an Unfavorable Outcome in Acute Coronary Syndrome Patients
por: Barbalata, Teodora, et al.
Publicado: (2023)

Hyperglycemia Determines Increased Specific MicroRNAs Levels in Sera and HDL of Acute Coronary Syndrome Patients and Stimulates MicroRNAs Production in Human Macrophages
por: Simionescu, Natalia, et al.
Publicado: (2016)

Increased miR-142 Levels in Plasma and Atherosclerotic Plaques from Peripheral Artery Disease Patients with Post-Surgery Cardiovascular Events
por: Barbalata, Teodora, et al.
Publicado: (2020)

Regulation of microRNAs in high-fat diet induced hyperlipidemic hamsters
por: Barbalata, Teodora, et al.
Publicado: (2020)

miR-146a-5p, miR-223-3p and miR-142-3p as Potential Predictors of Major Adverse Cardiac Events in Young Patients with Acute ST Elevation Myocardial Infarction—Added Value over Left Ventricular Myocardial Work Indices
por: Scărlătescu, Alina Ioana, et al.
Publicado: (2022)

Endothelial Dysfunction in Diabetes Is Aggravated by Glycated Lipoproteins; Novel Molecular Therapies
por: Toma, Laura, et al.
Publicado: (2020)

Dysfunctional high-density lipoproteins have distinct composition, diminished anti-inflammatory potential and discriminate acute coronary syndrome from stable coronary artery disease patients
por: Carnuta, Mihaela G., et al.
Publicado: (2017)

Formulation of Phytosomes with Extracts of Ginger Rhizomes and Rosehips with Improved Bioavailability, Antioxidant and Anti-Inflammatory Effects In Vivo
por: Deleanu, Mariana, et al.
Publicado: (2023)

MiR-486 and miR-92a Identified in Circulating HDL Discriminate between Stable and Vulnerable Coronary Artery Disease Patients
por: Niculescu, Loredan S., et al.
Publicado: (2015)

Ninjurin 1 contributes to TLR-induced inflammation in endothelial cells
por: Jennewein, C, et al.
Publicado: (2012)

Radiation Potentiates Monocyte Infiltration into Tumors by Ninjurin1 Expression in Endothelial Cells
por: Kang, Ju-Hee, et al.
Publicado: (2020)

Drosophila Ninjurin A Induces Nonapoptotic Cell Death
por: Broderick, Sarah, et al.
Publicado: (2012)

Ninjurin1 regulates striated muscle growth and differentiation
por: Kny, Melanie, et al.
Publicado: (2019)

Ninjurin2 overexpression promotes glioma cell growth
por: Zhou, Li-Na, et al.
Publicado: (2019)

AB171. Targeting Ninjurin-1 for future therapy of erectile dysfunction
por: Yin, Guo Nan, et al.
Publicado: (2014)

AB05. Targeting Ninjurin-1 for future therapy of erectile dysfunction
por: Suh, Jun Kyu
Publicado: (2014)

Ninjurin 2 rs118050317 gene polymorphism and endometrial cancer risk
por: Cheng, Yimin, et al.
Publicado: (2021)

Ninjurin1 positively regulates osteoclast development by enhancing the survival of prefusion osteoclasts
por: Bae, Sung-Jin, et al.
Publicado: (2019)

Muscimol inhibits plasma membrane rupture and ninjurin-1 oligomerization during pyroptosis
por: den Hartigh, Andreas B., et al.
Publicado: (2023)

Effect of irreversibly glycated LDL in human vascular smooth muscle cells: lipid loading, oxidative and inflammatory stress
por: Sima, Anca V, et al.
Publicado: (2010)

Ninjurin 2 overexpression promotes human colorectal cancer cell growth in vitro and in vivo
por: Li, Gang, et al.
Publicado: (2019)

Ninjurin-1: a biomarker for reflecting the process of neuroinflammation after spinal cord injury
por: Weerasinghe-Mudiyanselage, Poornima D. E., et al.
Publicado: (2020)

Elevated plasma Ninjurin-1 levels in atrial fibrillation is associated with atrial remodeling and thromboembolic risk
por: Fang, Chen, et al.
Publicado: (2022)

Ninjurin1 Deletion in NG2-Positive Pericytes Prevents Microvessel Maturation and Delays Wound Healing
por: Matsuo, Risa, et al.
Publicado: (2022)

Pericyte-Specific Ninjurin1 Deletion Attenuates Vessel Maturation and Blood Flow Recovery in Hind Limb Ischemia
por: Minoshima, Akiho, et al.
Publicado: (2018)

miR-125a-5p attenuates macrophage-mediated vascular dysfunction by targeting Ninjurin1
por: Hwang, Su Jung, et al.
Publicado: (2022)

Differential Expression of Nerve Injury-Induced Protein 1 (Ninjurin 1) in In Vivo and In Vitro Models for Diabetic Erectile Dysfunction
por: Kim, Do Kyung, et al.
Publicado: (2012)

Ninjurin1 Plays a Crucial Role in Pulmonary Fibrosis by Promoting Interaction between Macrophages and Alveolar Epithelial Cells
por: Choi, Seungho, et al.
Publicado: (2018)

Calcium/P53/Ninjurin 1 Signaling Mediates Plasma Membrane Rupture of Acinar Cells in Severe Acute Pancreatitis
por: Lee, Chehao, et al.
Publicado: (2023)

Ninjurin1 inhibits colitis-mediated colon cancer development and growth by suppression of macrophage infiltration through repression of FAK signaling
por: Woo, Jong Kyu, et al.
Publicado: (2016)

Association of serum Ninjurin2 levels with neurologic damage and postherpetic neuralgia occurrence: an observational cohort study in chinese herpeszoster patients
por: Zhang, Guozhuan, et al.
Publicado: (2017)

Genetic Polymorphisms of a Novel Vascular Susceptibility Gene, Ninjurin2 (NINJ2), Are Associated with a Decreased Risk of Alzheimer's Disease
por: Lin, Kun-Pei, et al.
Publicado: (2011)

Induction of Nerve Injury-Induced Protein 1 (Ninjurin 1) in Myeloid Cells in Rat Brain after Transient Focal Cerebral Ischemia
por: Lee, Hye-Kyung, et al.
Publicado: (2016)

Ninjurin 1 dodecamer peptide containing the N-terminal adhesion motif (N-NAM) exerts proangiogenic effects in HUVECs and in the postischemic brain
por: Kim, Seung-Woo, et al.
Publicado: (2020)

Deficiency of Ninjurin1 attenuates LPS/D‐galactosamine‐induced acute liver failure by reducing TNF‐α‐induced apoptosis in hepatocytes
por: Kim, Min Woo, et al.
Publicado: (2022)

Transcranial stimulation of alpha oscillations up-regulates the default mode network
por: Clancy, Kevin J., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_1r3ijv98tbiko7g7hjtv8pfb3k