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New Insights on Saporin Resistance to Chemical Derivatization with Heterobifunctional Reagents
Saporin is a type 1 ribosome-inactivating protein widely used as toxic payload in the construction of targeted toxins, chimeric molecules formed by a toxic portion linked to a carrier moiety. Among the most used carriers, there are large molecules (mainly antibodies) and small molecules (such as neu...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135674/ https://www.ncbi.nlm.nih.gov/pubmed/37189832 http://dx.doi.org/10.3390/biomedicines11041214 |