Pravastatin Prevents Increases in Activity of Metalloproteinase-2 and Oxidative Stress, and Enhances Endothelium-Derived Nitric Oxide-Dependent Vasodilation in Gestational Hypertension

Pre-eclampsia (PE) is a hypertensive disorder of pregnancy and has been associated with placental growth restriction. The pre-eclamptic placenta releases free radicals to maternal circulation, thus increasing oxidative stress. An impaired redox state leads to reduction in circulating nitric oxide (N...

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Detalles Bibliográficos
Autores principales: Toghi, Cristal Jesus, Martins, Laisla Zanetoni, Pacheco, Leonardo Lopes, Caetano, Edileia Souza Paula, Mattos, Bruna Rahal, Rizzi, Elen, Dias-Junior, Carlos Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135677/
https://www.ncbi.nlm.nih.gov/pubmed/37107314
http://dx.doi.org/10.3390/antiox12040939

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