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Mitochondria-Targeted Antioxidants as a Therapeutic Strategy for Chronic Obstructive Pulmonary Disease

Oxidative stress is a major hallmark of COPD, contributing to inflammatory signaling, corticosteroid resistance, DNA damage, and accelerated lung aging and cellular senescence. Evidence suggests that oxidative damage is not solely due to exogenous exposure to inhaled irritants, but also endogenous s...

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Detalles Bibliográficos
Autores principales: Fairley, Lauren H., Das, Shatarupa, Dharwal, Vivek, Amorim, Nadia, Hegarty, Karl J., Wadhwa, Ridhima, Mounika, Guntipally, Hansbro, Philip M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135688/
https://www.ncbi.nlm.nih.gov/pubmed/37107348
http://dx.doi.org/10.3390/antiox12040973