Cargando…

Mitochondria-Targeted Antioxidants as a Therapeutic Strategy for Chronic Obstructive Pulmonary Disease

Oxidative stress is a major hallmark of COPD, contributing to inflammatory signaling, corticosteroid resistance, DNA damage, and accelerated lung aging and cellular senescence. Evidence suggests that oxidative damage is not solely due to exogenous exposure to inhaled irritants, but also endogenous s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fairley, Lauren H., Das, Shatarupa, Dharwal, Vivek, Amorim, Nadia, Hegarty, Karl J., Wadhwa, Ridhima, Mounika, Guntipally, Hansbro, Philip M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135688/ https://www.ncbi.nlm.nih.gov/pubmed/37107348 http://dx.doi.org/10.3390/antiox12040973

Ejemplares similares

Role of Lung Microbiome in Innate Immune Response Associated With Chronic Lung Diseases
por: Paudel, Keshav Raj, et al.
Publicado: (2020)

The Role of Mitochondria and Oxidative/Antioxidative Imbalance in Pathobiology of Chronic Obstructive Pulmonary Disease
por: Białas, Adam Jerzy, et al.
Publicado: (2016)

Cellular mechanisms underlying steroid-resistant asthma
por: Wadhwa, Ridhima, et al.
Publicado: (2019)

Mitochondria Transfer in Brain Injury and Disease
por: Fairley, Lauren H., et al.
Publicado: (2022)

Poly(ADP-Ribose)Polymerase-1 in Lung Inflammatory Disorders: A Review
por: Sethi, Gurupreet S., et al.
Publicado: (2017)

Knowledge about obstructive sleep apnea among medical undergraduate students: A long way to go!
por: Wadhwa, Ridhima, et al.
Publicado: (2020)

Beyond antioxidants: Selenium and skeletal muscle mitochondria
por: Wesolowski, Lauren T., et al.
Publicado: (2022)

“KEAP”ing Alveolar Macrophage Mitochondria Content in Chronic Obstructive Pulmonary Disease
por: Cloonan, Suzanne M.
Publicado: (2023)

Steroid resistance and concomitant respiratory infections: A challenging battle in pulmonary clinic
por: Dua, Kamal, et al.
Publicado: (2017)

Intestinal obstruction associated with ovarian remnant in postmenopausal female
por: Gupta, Ridhima, et al.
Publicado: (2016)

Mapping the impact of COVID-19 crisis on the progress of sustainable Development Goals (SDGs) - a focus on global environment and energy efficiencies
por: Fulzele, Roopali, et al.
Publicado: (2022)

Morphometric analysis of mitochondria in lymphocytes of patients with exacerbations of chronic obstructive pulmonary disease – pilot study
por: Białas, Adam J, et al.
Publicado: (2018)

Development of hydroxybenzoic-based platforms as a solution to deliver dietary antioxidants to mitochondria
por: Teixeira, José, et al.
Publicado: (2017)

Total Antioxidant Status in Stable Chronic Obstructive Pulmonary Disease
por: Hlavati, Marina, et al.
Publicado: (2020)

Pulmonary-intestinal cross-talk in mucosal inflammatory disease
por: Keely, Simon, et al.
Publicado: (2011)

Mitochondria-targeted antioxidant effects of S(-) and R(+) pramipexole
por: Ferrari-Toninelli, Giulia, et al.
Publicado: (2010)

Mitochondria-Targeted Antioxidants and Skeletal Muscle Function
por: Broome, Sophie C., et al.
Publicado: (2018)

Mitochondria-targeted antioxidants as highly effective antibiotics
por: Nazarov, Pavel A., et al.
Publicado: (2017)

Pros and Cons of Use of Mitochondria-Targeted Antioxidants
por: Plotnikov, Egor Y., et al.
Publicado: (2019)

Mitochondrial Dysfunction and Oxidative Stress in Asthma: Implications for Mitochondria-Targeted Antioxidant Therapeutics
por: Reddy, P. Hemachandra
Publicado: (2011)

Disease-associated gut microbiome and metabolome changes in patients with chronic obstructive pulmonary disease
por: Bowerman, Kate L., et al.
Publicado: (2020)

Reactive Oxygen Species and Antioxidative Defense in Chronic Obstructive Pulmonary Disease
por: Taniguchi, Akihiko, et al.
Publicado: (2021)

Oligonucleotide therapy: An emerging focus area for drug delivery in chronic inflammatory respiratory diseases
por: Mehta, Meenu, et al.
Publicado: (2019)

Quantification and role of innate lymphoid cell subsets in Chronic Obstructive Pulmonary Disease
por: Blomme, Evy E, et al.
Publicado: (2021)

Bench-to-bedside review: Targeting antioxidants to mitochondria in sepsis
por: Galley, Helen F
Publicado: (2010)

Hormetic and Mitochondria-Related Mechanisms of Antioxidant Action of Phytochemicals
por: Franco, Rafael, et al.
Publicado: (2019)

Abnormal M1/M2 macrophage phenotype profiles in the small airway wall and lumen in smokers and chronic obstructive pulmonary disease (COPD)
por: Eapen, Mathew Suji, et al.
Publicado: (2017)

Mitochondria-targeted antioxidant therapy with MitoQ ameliorates aortic stiffening in old mice
por: Gioscia-Ryan, Rachel A., et al.
Publicado: (2018)

Roles for T/B lymphocytes and ILC2s in experimental chronic obstructive pulmonary disease
por: Donovan, Chantal, et al.
Publicado: (2018)

Understanding the mechanisms of viral induced asthma: New therapeutic directions
por: Hansbro, Nicole G., et al.
Publicado: (2008)

The Impact of Changes in the Intake of Fiber and Antioxidants on the Development of Chronic Obstructive Pulmonary Disease
por: Jung, Young Ju, et al.
Publicado: (2021)

Enhancing tristetraprolin activity reduces the severity of cigarette smoke‐induced experimental chronic obstructive pulmonary disease
por: Nair, Prema M, et al.
Publicado: (2019)

IL13 Promoter (−1055) Polymorphism Associated with Leukocyte Mitochondria DNA Copy Number in Chronic Obstructive Pulmonary Disease
por: Liu, Shih-Feng, et al.
Publicado: (2022)

Mitochondria-Targeted Antioxidants, an Innovative Class of Antioxidant Compounds for Neurodegenerative Diseases: Perspectives and Limitations
por: Fields, Matteo, et al.
Publicado: (2023)

Therapeutic Effect of the Mitochondria-Targeted Antioxidant SkQ1 on the Culture Model of Multiple Sclerosis
por: Fetisova, Elena K., et al.
Publicado: (2019)

Mitochondria-driven assembly of a cortical anchor for mitochondria and dynein
por: Kraft, Lauren M., et al.
Publicado: (2017)

Increased SARS-CoV-2 Infection, Protease, and Inflammatory Responses in Chronic Obstructive Pulmonary Disease Primary Bronchial Epithelial Cells Defined with Single-Cell RNA Sequencing
por: Johansen, Matt D., et al.
Publicado: (2022)

Effects of the Mitochondria-Targeted Antioxidant Mitoquinone in Murine Acute Pancreatitis
por: Huang, Wei, et al.
Publicado: (2015)

Synthesis of triphenylphosphonium vitamin E derivatives as mitochondria-targeted antioxidants
por: Jameson, Victoria J.A., et al.
Publicado: (2015)

Mitochondria: Central Organelles for Melatonin′s Antioxidant and Anti-Aging Actions
por: Reiter, Russel J., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_2hdcunct0gb259g37scrs8u6lt