Cargando…

Biological Role and Aberrant Overexpression of Syntenin-1 in Cancer: Potential Role as a Biomarker and Therapeutic Target

Syntenin-1 is a 298 amino acid protein codified by the melanoma differentiation-associated gene-9 (MDA-9). Structurally, it is composed of four domains: N-terminal, PDZ1, PDZ2, and C-terminal. The PDZ domains of syntenin-1 are involved in the stability and interaction with other molecules such as pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Pintor-Romero, Valeria Guadalupe, Hurtado-Ortega, Edgar, Nicolás-Morales, María Lilia, Gutiérrez-Torres, Mayralina, Vences-Velázquez, Amalia, Ortuño-Pineda, Carlos, Espinoza-Rojo, Mónica, Navarro-Tito, Napoleón, Cortés-Sarabia, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135703/
https://www.ncbi.nlm.nih.gov/pubmed/37189651
http://dx.doi.org/10.3390/biomedicines11041034