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Virtual and In Vitro Screening of Natural Products Identifies Indole and Benzene Derivatives as Inhibitors of SARS-CoV-2 Main Protease (M(pro))

SIMPLE SUMMARY: The coronavirus disease 2019 (COVID-19) pandemic caused more than 6.7 million deaths worldwide. Certain groups of individuals are still at a high risk of severe illness. The availability of drugs to treat COVID-19 symptoms will save many lives. The main protease (M(pro)) of SARS-CoV2...

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Detalles Bibliográficos
Autores principales: Ang, Dony, Kendall, Riley, Atamian, Hagop S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135783/
https://www.ncbi.nlm.nih.gov/pubmed/37106720
http://dx.doi.org/10.3390/biology12040519