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Artificial Intelligence Assisted Pharmacophore Design for Philadelphia Chromosome-Positive Leukemia with Gamma-Tocotrienol: A Toxicity Comparison Approach with Asciminib

BCR-ABL1 is a fusion protein as a result of a unique chromosomal translocation (producing the so-called Philadelphia chromosome) that serves as a clinical biomarker primarily for chronic myeloid leukemia (CML); the Philadelphia chromosome also occurs, albeit rather rarely, in other types of leukemia...

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Detalles Bibliográficos
Autores principales: Naveed, Muhammad, Ain, Noor ul, Aziz, Tariq, Javed, Khushbakht, Shabbir, Muhammad Aqib, Alharbi, Metab, Alsahammari, Abdulrahman, Alasmari, Abdullah F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135824/
https://www.ncbi.nlm.nih.gov/pubmed/37189659
http://dx.doi.org/10.3390/biomedicines11041041