Obesity-Linked PPARγ Ser273 Phosphorylation Promotes Beneficial Effects on the Liver, despite Reduced Insulin Sensitivity in Mice

Since the removal of thiazolidinediones (TZDs) from the market, researchers have been exploring alternative anti-diabetic drugs that target PPARγ without causing adverse effects while promoting insulin sensitization by blocking serine 273 phosphorylation (Ser273 or S273). Nonetheless, the underlying...

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Detalles Bibliográficos
Autores principales: Terra, Maiara Ferreira, García-Arévalo, Marta, Avelino, Thayná Mendonça, Degaki, Karina Y., de Carvalho, Murilo, Torres, Felipe Rafael, Saito, Angela, Figueira, Ana Carolina Migliorini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135908/
https://www.ncbi.nlm.nih.gov/pubmed/37189379
http://dx.doi.org/10.3390/biom13040632

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