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Somatic Copy Number Alteration in Circulating Tumor DNA for Monitoring of Pediatric Patients with Cancer

Pediatric tumors share few recurrent mutations and are instead characterized by copy number alterations (CNAs). The cell-free DNA (cfDNA) is a prominent source for the detection of cancer-specific biomarkers in plasma. We profiled CNAs in the tumor tissues for further evaluation of alterations in 1q...

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Detalles Bibliográficos
Autores principales: Ruas, Juliana Silveira, Silva, Felipe Luz Torres, Euzébio, Mayara Ferreira, Biazon, Tássia Oliveira, Daiggi, Camila Maia Martin, Nava, Daniel, Franco, Mayra Troiani, Cardinalli, Izilda Aparecida, Cassone, Alejandro Enzo, Pereira, Luiz Henrique, Seidinger, Ana Luiza, Maschietto, Mariana, Jotta, Patricia Yoshioka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135914/
https://www.ncbi.nlm.nih.gov/pubmed/37189699
http://dx.doi.org/10.3390/biomedicines11041082