Cargando…

Advanced Urea Precursors Driven NiCo(2)O(4) Nanostructures Based Non-Enzymatic Urea Sensor for Milk and Urine Real Sample Applications

The electrochemical performance of NiCo(2)O(4) with urea precursors was evaluated in order to develop a non-enzymatic urea sensor. In this study, NiCo(2)O(4) nanostructures were synthesized hydrothermally at different concentrations of urea and characterized using scanning electron microscopy and X-...

Descripción completa

Detalles Bibliográficos
Autores principales: Mangrio, Sanjha, Tahira, Aneela, Chang, Abdul Sattar, Mahar, Ihsan Ali, Markhand, Mehnaz, Shah, Aqeel Ahmed, Medany, Shymaa S., Nafady, Ayman, Dawi, Elmuez A., Saleem, Lama M. A., Mustafa, E. M., Vigolo, Brigitte, Ibupoto, Zafar Hussain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135918/
https://www.ncbi.nlm.nih.gov/pubmed/37185519
http://dx.doi.org/10.3390/bios13040444
_version_ 1785032095270174720
author Mangrio, Sanjha
Tahira, Aneela
Chang, Abdul Sattar
Mahar, Ihsan Ali
Markhand, Mehnaz
Shah, Aqeel Ahmed
Medany, Shymaa S.
Nafady, Ayman
Dawi, Elmuez A.
Saleem, Lama M. A.
Mustafa, E. M.
Vigolo, Brigitte
Ibupoto, Zafar Hussain
author_facet Mangrio, Sanjha
Tahira, Aneela
Chang, Abdul Sattar
Mahar, Ihsan Ali
Markhand, Mehnaz
Shah, Aqeel Ahmed
Medany, Shymaa S.
Nafady, Ayman
Dawi, Elmuez A.
Saleem, Lama M. A.
Mustafa, E. M.
Vigolo, Brigitte
Ibupoto, Zafar Hussain
author_sort Mangrio, Sanjha
collection PubMed
description The electrochemical performance of NiCo(2)O(4) with urea precursors was evaluated in order to develop a non-enzymatic urea sensor. In this study, NiCo(2)O(4) nanostructures were synthesized hydrothermally at different concentrations of urea and characterized using scanning electron microscopy and X-ray diffraction. Nanostructures of NiCo(2)O(4) exhibit a nanorod-like morphology and a cubic phase crystal structure. Urea can be detected with high sensitivity through NiCo(2)O(4) nanostructures driven by urea precursors under alkaline conditions. A low limit of detection of 0.05 and an analytical range of 0.1 mM to 10 mM urea are provided. The concentration of 006 mM was determined by cyclic voltammetry. Chronoamperometry was used to determine the linear range in the range of 0.1 mM to 8 mM. Several analytical parameters were assessed, including selectivity, stability, and repeatability. NiCo(2)O(4) nanostructures can also be used to detect urea in various biological samples in a practical manner.
format Online
Article
Text
id pubmed-10135918
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-101359182023-04-28 Advanced Urea Precursors Driven NiCo(2)O(4) Nanostructures Based Non-Enzymatic Urea Sensor for Milk and Urine Real Sample Applications Mangrio, Sanjha Tahira, Aneela Chang, Abdul Sattar Mahar, Ihsan Ali Markhand, Mehnaz Shah, Aqeel Ahmed Medany, Shymaa S. Nafady, Ayman Dawi, Elmuez A. Saleem, Lama M. A. Mustafa, E. M. Vigolo, Brigitte Ibupoto, Zafar Hussain Biosensors (Basel) Article The electrochemical performance of NiCo(2)O(4) with urea precursors was evaluated in order to develop a non-enzymatic urea sensor. In this study, NiCo(2)O(4) nanostructures were synthesized hydrothermally at different concentrations of urea and characterized using scanning electron microscopy and X-ray diffraction. Nanostructures of NiCo(2)O(4) exhibit a nanorod-like morphology and a cubic phase crystal structure. Urea can be detected with high sensitivity through NiCo(2)O(4) nanostructures driven by urea precursors under alkaline conditions. A low limit of detection of 0.05 and an analytical range of 0.1 mM to 10 mM urea are provided. The concentration of 006 mM was determined by cyclic voltammetry. Chronoamperometry was used to determine the linear range in the range of 0.1 mM to 8 mM. Several analytical parameters were assessed, including selectivity, stability, and repeatability. NiCo(2)O(4) nanostructures can also be used to detect urea in various biological samples in a practical manner. MDPI 2023-03-31 /pmc/articles/PMC10135918/ /pubmed/37185519 http://dx.doi.org/10.3390/bios13040444 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Mangrio, Sanjha
Tahira, Aneela
Chang, Abdul Sattar
Mahar, Ihsan Ali
Markhand, Mehnaz
Shah, Aqeel Ahmed
Medany, Shymaa S.
Nafady, Ayman
Dawi, Elmuez A.
Saleem, Lama M. A.
Mustafa, E. M.
Vigolo, Brigitte
Ibupoto, Zafar Hussain
Advanced Urea Precursors Driven NiCo(2)O(4) Nanostructures Based Non-Enzymatic Urea Sensor for Milk and Urine Real Sample Applications
title Advanced Urea Precursors Driven NiCo(2)O(4) Nanostructures Based Non-Enzymatic Urea Sensor for Milk and Urine Real Sample Applications
title_full Advanced Urea Precursors Driven NiCo(2)O(4) Nanostructures Based Non-Enzymatic Urea Sensor for Milk and Urine Real Sample Applications
title_fullStr Advanced Urea Precursors Driven NiCo(2)O(4) Nanostructures Based Non-Enzymatic Urea Sensor for Milk and Urine Real Sample Applications
title_full_unstemmed Advanced Urea Precursors Driven NiCo(2)O(4) Nanostructures Based Non-Enzymatic Urea Sensor for Milk and Urine Real Sample Applications
title_short Advanced Urea Precursors Driven NiCo(2)O(4) Nanostructures Based Non-Enzymatic Urea Sensor for Milk and Urine Real Sample Applications
title_sort advanced urea precursors driven nico(2)o(4) nanostructures based non-enzymatic urea sensor for milk and urine real sample applications
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135918/
https://www.ncbi.nlm.nih.gov/pubmed/37185519
http://dx.doi.org/10.3390/bios13040444
work_keys_str_mv AT mangriosanjha advancedureaprecursorsdrivennico2o4nanostructuresbasednonenzymaticureasensorformilkandurinerealsampleapplications
AT tahiraaneela advancedureaprecursorsdrivennico2o4nanostructuresbasednonenzymaticureasensorformilkandurinerealsampleapplications
AT changabdulsattar advancedureaprecursorsdrivennico2o4nanostructuresbasednonenzymaticureasensorformilkandurinerealsampleapplications
AT maharihsanali advancedureaprecursorsdrivennico2o4nanostructuresbasednonenzymaticureasensorformilkandurinerealsampleapplications
AT markhandmehnaz advancedureaprecursorsdrivennico2o4nanostructuresbasednonenzymaticureasensorformilkandurinerealsampleapplications
AT shahaqeelahmed advancedureaprecursorsdrivennico2o4nanostructuresbasednonenzymaticureasensorformilkandurinerealsampleapplications
AT medanyshymaas advancedureaprecursorsdrivennico2o4nanostructuresbasednonenzymaticureasensorformilkandurinerealsampleapplications
AT nafadyayman advancedureaprecursorsdrivennico2o4nanostructuresbasednonenzymaticureasensorformilkandurinerealsampleapplications
AT dawielmueza advancedureaprecursorsdrivennico2o4nanostructuresbasednonenzymaticureasensorformilkandurinerealsampleapplications
AT saleemlamama advancedureaprecursorsdrivennico2o4nanostructuresbasednonenzymaticureasensorformilkandurinerealsampleapplications
AT mustafaem advancedureaprecursorsdrivennico2o4nanostructuresbasednonenzymaticureasensorformilkandurinerealsampleapplications
AT vigolobrigitte advancedureaprecursorsdrivennico2o4nanostructuresbasednonenzymaticureasensorformilkandurinerealsampleapplications
AT ibupotozafarhussain advancedureaprecursorsdrivennico2o4nanostructuresbasednonenzymaticureasensorformilkandurinerealsampleapplications