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Expression of a Siglec-Fc Protein and Its Characterization

SIMPLE SUMMARY: The Siglec-Fc protein, a fusion protein combining Siglec with the Fc part of a human antibody, is a promising sialic acid-Siglec axis-targeted agent for cancer treatment and is widely used for Siglec ligands discovery. The recombinant Siglec-Fc fusion protein has been expressed in di...

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Detalles Bibliográficos
Autores principales: Chi, Kaijun, Xu, Huilin, Li, Hanjie, Yang, Ganglong, Zhou, Xiaoman, Gao, Xiao-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135921/
https://www.ncbi.nlm.nih.gov/pubmed/37106774
http://dx.doi.org/10.3390/biology12040574