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Human Microglia Synthesize Neurosteroids to Cope with Rotenone-Induced Oxidative Stress

We obtained evidence that mouse BV2 microglia synthesize neurosteroids dynamically to modify neurosteroid levels in response to oxidative damage caused by rotenone. Here, we evaluated whether neurosteroids could be produced and altered in response to rotenone by the human microglial clone 3 (HMC3) c...

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Detalles Bibliográficos
Autores principales: Lucchi, Chiara, Codeluppi, Alessandro, Filaferro, Monica, Vitale, Giovanni, Rustichelli, Cecilia, Avallone, Rossella, Mandrioli, Jessica, Biagini, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10135967/
https://www.ncbi.nlm.nih.gov/pubmed/37107338
http://dx.doi.org/10.3390/antiox12040963