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Reactive Oxygen Species Regulation of Chemoresistance and Metastatic Capacity of Melanoma: Role of the Cancer Stem Cell Marker CD271

BRAF mutations are present in 30–50% of cases of cutaneous melanoma, and treatment with selective BRAF and MEK inhibitors has been introduced. However, the development of resistance to these drugs often occurs. Chemo-resistant melanoma cells show increased expression of CD271, a stem cell marker tha...

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Detalles Bibliográficos
Autores principales: Beretti, Francesca, Gatti, Martina, Zavatti, Manuela, Bassoli, Sara, Pellacani, Giovanni, Maraldi, Tullia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136133/
https://www.ncbi.nlm.nih.gov/pubmed/37189846
http://dx.doi.org/10.3390/biomedicines11041229