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Inhibition Analysis and High-Resolution Crystal Structure of Mus musculus Glutathione Transferase P1-1

Multidrug resistance is a significant barrier that makes anticancer therapies less effective. Glutathione transferases (GSTs) are involved in multidrug resistance mechanisms and play a significant part in the metabolism of alkylating anticancer drugs. The purpose of this study was to screen and sele...

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Detalles Bibliográficos
Autores principales: Kupreienko, Oleksii, Pouliou, Fotini, Konstandinidis, Konstantinos, Axarli, Irene, Douni, Eleni, Papageorgiou, Anastassios C., Labrou, Nikolaos E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136361/
https://www.ncbi.nlm.nih.gov/pubmed/37189361
http://dx.doi.org/10.3390/biom13040613