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Inhibition Analysis and High-Resolution Crystal Structure of Mus musculus Glutathione Transferase P1-1
Multidrug resistance is a significant barrier that makes anticancer therapies less effective. Glutathione transferases (GSTs) are involved in multidrug resistance mechanisms and play a significant part in the metabolism of alkylating anticancer drugs. The purpose of this study was to screen and sele...
Autores principales: | Kupreienko, Oleksii, Pouliou, Fotini, Konstandinidis, Konstantinos, Axarli, Irene, Douni, Eleni, Papageorgiou, Anastassios C., Labrou, Nikolaos E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136361/ https://www.ncbi.nlm.nih.gov/pubmed/37189361 http://dx.doi.org/10.3390/biom13040613 |
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