Cyclic GMP–AMP Synthase (cGAS) Deletion Reduces Severity in Bilateral Nephrectomy Mice through Changes in Neutrophil Extracellular Traps and Mitochondrial Respiration

Uremia-induced systemic inflammation is partly caused by the dissemination of microbial molecules such as lipopolysaccharide and bacterial double-stranded DNA from leaked gut damaged by immune cells in response to the microbial molecules. Cyclic GMP–AMP synthase (cGAS) can recognize fragmented DNA a...

Descripción completa

Detalles Bibliográficos
Autores principales: Suksawad, Nattavong, Udompornpitak, Kanyarat, Thawinpipat, Natchapon, Korwattanamongkol, Pichaya, Visitchanakun, Peerapat, Phuengmaung, Pornpimol, Saisorn, Wilasinee, Kueanjinda, Patipark, Leelahavanichkul, Asada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136362/
https://www.ncbi.nlm.nih.gov/pubmed/37189826
http://dx.doi.org/10.3390/biomedicines11041208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136362/
https://www.ncbi.nlm.nih.gov/pubmed/37189826
http://dx.doi.org/10.3390/biomedicines11041208

Ejemplares similares