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Cyclic GMP–AMP Synthase (cGAS) Deletion Reduces Severity in Bilateral Nephrectomy Mice through Changes in Neutrophil Extracellular Traps and Mitochondrial Respiration

Uremia-induced systemic inflammation is partly caused by the dissemination of microbial molecules such as lipopolysaccharide and bacterial double-stranded DNA from leaked gut damaged by immune cells in response to the microbial molecules. Cyclic GMP–AMP synthase (cGAS) can recognize fragmented DNA a...

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Detalles Bibliográficos
Autores principales:	Suksawad, Nattavong, Udompornpitak, Kanyarat, Thawinpipat, Natchapon, Korwattanamongkol, Pichaya, Visitchanakun, Peerapat, Phuengmaung, Pornpimol, Saisorn, Wilasinee, Kueanjinda, Patipark, Leelahavanichkul, Asada
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136362/ https://www.ncbi.nlm.nih.gov/pubmed/37189826 http://dx.doi.org/10.3390/biomedicines11041208

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