Cargando…

Lung Micrometastases Display ECM Depletion and Softening While Macrometastases Are 30-Fold Stiffer and Enriched in Fibronectin

SIMPLE SUMMARY: This study examined the mechanical properties of the extracellular matrix (ECM) in lung metastases from two cancer models: lung carcinoma and melanoma. The ECM is the framework that holds tissues and organs together in the body. The researchers found that the ECM in the metastases wa...

Descripción completa

Detalles Bibliográficos
Autores principales: Narciso, Maria, Martínez, África, Júnior, Constança, Díaz-Valdivia, Natalia, Ulldemolins, Anna, Berardi, Massimiliano, Neal, Kate, Navajas, Daniel, Farré, Ramon, Alcaraz, Jordi, Almendros, Isaac, Gavara, Núria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136590/
https://www.ncbi.nlm.nih.gov/pubmed/37190331
http://dx.doi.org/10.3390/cancers15082404