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Ibrutinib Inhibits BTK Signaling in Tumor-Infiltrated B Cells and Amplifies Antitumor Immunity by PD-1 Checkpoint Blockade for Metastatic Prostate Cancer
SIMPLE SUMMARY: Metastatic prostate cancer has a poor clinical prognosis and is incurable. In recent decades, immune checkpoint blockade has revolutionized anticancer therapies and represents a potential way to control metastatic prostate cancer. Unfortunately, due to low immunoreactivity, patients...
Autores principales: | Deng, Gengguo, He, Jiannan, Huang, Qunxiong, Li, Tengcheng, Huang, Zhansen, Gao, Shuntian, Xu, Jinbin, Wang, Tiantian, Di, Jinming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10136622/ https://www.ncbi.nlm.nih.gov/pubmed/37190284 http://dx.doi.org/10.3390/cancers15082356 |
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